Need To Know.

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Cannabinoid receptor type 1 (CB₁) is a G protein-coupled cannabinoid receptor located primarily in the central and peripheral nervous system. It is activated by the endocannabinoid neurotransmitters (anandamide and 2-arachidonoyl glyceride); by plant cannabinoids (e.g. Tetrahydrocannabinol); or by synthetic analogues of THC (e.g. dronabinol).

Cannabinoid receptor type 2 (CB₂), also, is a G protein-coupled receptor from the cannabinoid receptor family. Cannabinoid receptor type 2 is closely related to cannabinoid receptor type 1.

Read more about CB₁ and CB_2.

EGF.

Epidermal growth factor (EGF) is a growth factor that stimulates cell growth, proliferation and differentiation, by binding to its receptor, epidermal growth receptor. EGF and its receptor were discovered by Stanley Cohen of Vanderbilt University.

EGF is a low-molecular-weight polypeptide. The human EGF is a 6045-Da protein with 53 amino acid residues and three intramolecular disulfide bonds. It can be found in human platelets, macrophages, urine, saliva, milk and plasma.

Source: Wikipedia.

EGFR.

Epidermal growth factor receptor (EGFR) is the cell-surface receptor for members of the epidermal growth factor family of extracellular protein ligands. It is activated by binding of its ligands, including EGF and transforming growth factor α (TGFα).

Source: Wikipedia.